THE HISTOLOGICAL CHANGES PRODUCED BY RICIN AND ABRIN INTOXICATIONS
نویسندگان
چکیده
منابع مشابه
The Histological Changes Produced by Ricin and Abrin Intoxications
The study of the effects of the living pathogenic organisms upon the animal body has been succeeded by an era in which especial attent-ion has been directed to the influence of their soluble products. The researches of Oertel* upon human diphtheria, of Babes t and of Welch and Flexner$ upon the experimental form of the disease, the latter including the effects of the soluble products of the gro...
متن کاملToxicity and detection of ricin and abrin in beverages.
The oral and intraperitoneal (i.p.) toxicities to female BALB/c mice of ricin and abrin in phosphate-buffered saline (PBS), spring water, apple juice, and half-and-half (only oral) were examined after brief (2 h) and prolonged (11 to 13 days) storage. The ricin and abrin samples prepared in PBS had oral toxicities consistent with those previous studies, indicating oral and i.p. 50% lethal doses...
متن کاملThe binding of abrin and ricin by Ehrlich ascites tumor cells.
teins on the tumor cells was shown to be specific, pH de pendent, and concentration dependent. Native ricin, abrin, D-galactose, and its sterically related saccharides inhibit this specific binding, while concanavalin A, bovine serum albumin, heat-denatured abrin or ricin, and other sac charides do not. In the presence of D-galactose, the inhibi tion of protein biosynthesis by ricin does not oc...
متن کاملThe Binding of Abrin and Ricin by Ehrlich Ascites Tumor Cells1
teins on the tumor cells was shown to be specific, pH de pendent, and concentration dependent. Native ricin, abrin, D-galactose, and its sterically related saccharides inhibit this specific binding, while concanavalin A, bovine serum albumin, heat-denatured abrin or ricin, and other sac charides do not. In the presence of D-galactose, the inhibi tion of protein biosynthesis by ricin does not oc...
متن کاملSimultaneous Detection of Ricin and Abrin DNA by Real-Time PCR (qPCR)
Ricin and abrin are two of the most potent plant toxins known and may be easily obtained in high yield from the seeds using rather simple technology. As a result, both toxins are potent and available toxins for criminal or terrorist acts. However, as the production of highly purified ricin or abrin requires sophisticated equipment and knowledge, it may be more likely that crude extracts would b...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1897
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2.2.197